Chemistry

Conferences & Courses
Discovery on Target Discovery on Target
September 21-24, 2015 | Boston, MA
Cambridge Healthtech Institute will host its 13th Annual Discovery on Target event showcasing current and emerging “hot” targets for the pharmaceutical industry September 21-24, 2015 in Boston, MA.

GPCR-Based Drug Discovery Part 1 GPCR-Based Drug Discovery Part 1
September 22-23, 2015 | Boston, MA
Despite their fruitful history in the drug development industry, discovering or designing new therapeutic agents that modulate a GPCR in a specific way is still a challenge, and in fact is undergoing a renewal because of explosion of new knowledge about t

Targeting Epigenetic Readers and Chromatin Remodelers Targeting Epigenetic Readers and Chromatin Remodelers
September 22-23, 2015 | Boston, MA
Discovery on Target's Targeting Epigenetic Readers and Chromatin Remodelers meeting unites academic and industry researchers for the development of chemical probes, to discuss advances in preclinical and clinical programs, and ultimately further the u




Life Science Media Library
Trends in Physical Properties of Drugs Trends in Physical Properties of Drugs
April 22, 2014 |
The physical properties of drugs influence all aspects of their discovery, development, formulation, and administration. They are key to efficacy, effective assays, and in vivo delivery. This course will discuss latest trends and state-of-the art of prediction and measurement of key properties. Properties important for enhanced efficacy, delivery, and formulation pKa, tautomerism, crystallization, others Computational prediction: What works - what doesn’t Experimental best practices
PK/PD Bioanalysis PK/PD Bioanalysis
October 12, 2012 |
Novel constructs, such as anti-drug conjugates (ADCs) and bispecific antibodies, now exist as promising candidates in biotherapeutic pipelines. With aggressive timelines and contraction in the biopharma labor force, assay development can pose challenges beyond typical assays for pharmacokinetics and pharmacodynamics. Several bioanalytical techniques can be employed to measure these novel constructs. This short course will cover assay technologies to measure ADCs and bi-specific antibody therapeutics for pharmacokinetics and pharmacodynamics presented by various biopharma scientists.
Clinical Assay Development Clinical Assay Development
September 19, 2012 |
Presentations selected from the Clinical Assay Development workshop at the Fourth Annual ADAPT Congress 2012 discuss how discovery and research assays are increasingly being converted into clinically useful assays that are used in clinical trials to improve patient outcome and to support drug development. Regulatory issues and the dedication of resources to develop assays are addressed, as well as strategies to overcome the challenges of using commercial assays on clinical samples; analytical validation studies to determine clinical utility; and the benefits of working with a diagnostics organization with both experienced IVD manufacturing and an extensive CLIA laboratory infrastructure.




Publications, Reports, & Whitepapers
Vaccines: The End of Illness
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.
Macrocycles: Discovery, Development & Technologies
New to Insight Pharma Reports is Macrocycles: Discovery, Development & Technologies covers background material including a more in depth analysis of what macrocycles are and the pharmacokinetic properties (absorption, distribution, metabolism, and excretion) they exhibit. Challenges, benefits, and additional properties that are considered with their development as drugs are covered as well.
Back-Up Compound Strategies
Backup Compound Strategies: Commercial and Tactical Considerations, published by Insight Pharma Reports.
Fragment-Based Drug Discovery
Fragment-Based Drug Discovery: Technologies, Applications, and Pipelines, published by Insight Pharma Reports.
High-Content Analysis Report
High-Content Analysis: Technologies, Applications, and Market Dynamics, pubished by Insight Pharma Reports focuses on the applications, technology and market aspects of high-content analysis (HCA).
Medicinal Chemistry for Drug Discovery: Significance of Recent Trends
This report analyzes recent trends in medicinal chemistry and evaluates their significance for advancing R&D productivity. We consider technological modalities and market dynamics, with an emphasis on outsourcing and user views on the implications of current practices.
Blood-Brain Barrier: Bridging Options for Drug Discovery & Development
This report reviews the discovery, design, and development of small- and large-molecule drugs that can efficiently cross the blood-brain barrier.













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